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Special Notices (update date descending order)

IMC Version 9.4.0 Release Notes

Category: IMC Release News
Also available: 日本語 (Japan)

The latest IMC Version 9.4.0 installer for Windows has been released.

The latest IMC Version 9.4.0 installer for macOS has been released.

  • macOS 13 (Ventura), 14 (Sonoma), 15 (Sequoia), 26 (Tahoe), 27 (Golden Gate; if you use an LDK license, you may need to install Rosetta 2. See details here)
  • Windows 11

New Features, Feature Changes/Improvements, Bug Fixes

New Features

  • Added support for importing GeneMark.hmm prediction results (amino acid FASTA).

Feature Changes/Improvements

  • Removed the Send to PlasmidMap button from the Fragment Table.

Bug Fixes

  • Fixed a bug that prevented LDK license recognition on macOS 26 Tahoe.
  • Fixed a bug where the scrollbar did not reach the end in PlasmidMap.
  • Fixed a bug in the initial display of the Product Filter in Multi Fragment Assembly.
  • Corrected inaccurate descriptions of Assembly methods.
Hits: 442

Important Note When Upgrading to macOS 27 (Golden Gate)

Category: Special Notices
Also available: 日本語 (Japan)

After upgrading to macOS 27, your LDK dongle (HardKey license) may not be recognized, and IMC may fall back to a software key license instead. This happens because Rosetta 2 - the compatibility layer that runs Intel-built software on Apple Silicon - is not installed by default on macOS 27.

If your dongle is not recognized, install Rosetta 2 as follows:

  1. Open the Terminal app
  2. Run the following command:
    softwareupdate --install-rosetta --agree-to-license
  3. Restart IMC
Hits: 677

IMC Version 9.3.0 Release Notes

Category: IMC Release News
Also available: 日本語 (Japan)

The latest IMC Version 9.3.0 installer for Windows has been released.

The latest IMC Version 9.3.0 installer for macOS has been released.

  • macOS 13 (Ventura), 14 (Sonoma), 15 (Sequoia), 26 (Tahoe, SoftKey License Only)
  • Windows 11

New Features, Feature Changes/Improvements, Bug Fixes

New Features

  • Cloning Workbench (beta)
  • Integrated (Multiple) Ligation (beta)
  • Ligation Simulation (beta)
  • Graphical Tools for Ligation (beta)
  • New Plasmid Map (beta)
  • Fragment Assembly Primer Design (beta)
    • Golden Gate Assembly, etc.
  • Construct Canvas (beta)
  • DNA Fragment Assembly Workbench
  • Added FBA and FVA to the Metabolic Pathway feature (beta)
  • FBA/FVA results can now be shown as a series graph overlay on the Metabolic Pathway Canvas (beta)
  • Added a sample Genome Scale Model install option
    • If you do not need the Genome Scale Model, please delete the model file.

Feature Changes/Improvements

  • Significantly reduced IMC startup time
  • You can now choose to show or hide each button individually, and change its display order within its group.
  • Slightly adjusted the layout of the Cloning Workbench.
  • Added the New Plasmid Map feature.
  • Improved the Primer Design feature for Fragment Assembly.

Bug Fixes

  • Fixed an issue where the state transitions of the Tool buttons on the Top, Bottom, Left, and Right of the Main Window were incorrect.
  • Fixed several minor bugs in IMC.
Hits: 3065

New Server Deployment of www.insilico-biology.com site

Category: Site
Also available: 日本語 (Japan)

Due to issues that occurred earlier this week, we have been working on migrating our website to a new server. As the restoration of functionality has been largely completed, the site is now back online on the new server as of today.

We acknowledge that this may have caused inconvenience for some users.

www.insilico-biology.com

in silico biology, Inc.

Hits: 12443

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